XtimateTM is Welch Materials’n ew premium HPLC column series. XtimateTM is the product of several years of continuous research on advanced surface modifi cation at Welch Materials, Inc. There are two types of Xtimate HPLC columns, those based on Hybrid Silica-Polymer packing materials, and those based on pure polymer media.

Compared to mid-range priced Ultisil® series of premium quality, hybrid silica-polymer particles based XtimateTM HPLC columns are our next generation products with superior performance, especially excellent peak shape for strong bases, and extended lifetime at high pH range, making those columns most universal HPLC columns for a wide pH range applications.

Hybrid silica-polymer particles based XtimateTM particles are based on our best seller Ultisil® series ultra high purity silica particles, but the surface is further modifi ed with a unique hybrid organic/inorganic polymer using our state-of-art SmoothCoatTM surface modification technique; as a result, the hybrid silica-polymer particles based XtimateTM particles exhibit both silica particle properties of high mechanic strength and high effi ciency and organic polymer properties of inertness and resistance to alkali dissolution. Hybrid silica-polymer particles based XtimateTM HPLC columns represent our world leading technology of high premium and high quality HPLC columns in the market.

Besides hybrid surface on silica materials, we also developed PS/DVB polymer based materials for saccharide separation in XtimateTM columns, including Saccharide-H and Saccharide-Ca.

Characteristics of hybrid particles based XtimateTM columns:
» Wide pH range from 1.0 to 12.5
» Silica particle properties of high mechanic strength and high effi ciency and organic polymer properties of inertness and resistance to alkali dissolution
» Long column lifetime：5 times of similar product such as Gemini
» Excellent peak shape for strong bases

Hybrid particles based XtimateTM HPLC columns are designed for wide pH application, especially for high pH application because of their unprecedented long lifetime at high pH. Hybrid particles based XtimateTM HPLC columns can be used at any mobile phase composition and high temperature condition. They don’t exhibit phase collapse even at 100% aqueous mobile phase condition. Even under extreme conditions, the hybrid particles based XtimateTM HPLC columns will still exhibit excellent performance, making hybrid particles based XtimateTM HPLC columns the most reliable solution for the most diffi cult separation.

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